Endothelial Dysfunction in Coronavirus disease: A Literature Review

نویسندگان

چکیده

Coronavirus disease (COVID-19), caused by Sars-Cov-2, affects several cell types, including the vascular endothelium, which can lead to immunological phenomena and coagulopathies with systemic lesions. Thus, objective was describe, through a bibliographic review, endothelial dysfunction induced coronavirus. The data collected in this study suggest that lesion of endothelium coronavirus leads death exposure glycocalyx, resulting activation neutrophils platelets, consequent production cytokines blood clotting, inducing formation thrombi / clots . consequences are hypoxia widespread lesions organs, life-threatening patients COVID-19. Endothelial is well established cardiovascular diseases diabetes, such way these comorbidities could aggravate endothelium-induced more serious clinical outcomes. close relationship observed between dysfunctions COVID-19 inflammatory thrombotic events, worsening cases fatal early diagnosis assist therapy stabilizes reduces aggravation risk death, especially chronic diabetes.

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ژورنال

عنوان ژورنال: Journal of health science research

سال: 2021

ISSN: ['2456-2688']

DOI: https://doi.org/10.7324/jhsr.2021.615